Hi,
1. What is the model of the HDD drive as well
2. Can you make sure that all of your drives on this machine are fully up to date.
3. Can you post commands:
pgpwde.exe --enum
pgpwde.exe --status
pgpwde.exe --list-users
4. Can you post partition structure from computer management or via diskpart command
5. How the disk is visible on PGP as 'Unknown Bus' or 'Fixed Drive'
6. Can you also try to run the pgpwde.exe command to encrypt the drive from the command line and send a feedback.
pgpwde.exe --encrypt --disk 0 --passphrase "xxxxx"
HTH