I haven't succeeded yet.
https://www-secure.symantec.com/connect/forums/sep-clustered-exchange

I guess I can only try to find out....  Any one has suggestion ?

Please check this KB,

http://service1.symantec.com/support/ent-security....

I am using VCS cluster for the SQL 2005 database in each site and two Symantec EP management servers for load balancing, I also choose ring topology fro database replication once a day. so far all worked well and I have not seen any issue with this design. The reason I chose Veritas cluster not Microsoft cluster, majorly is cost concern.  

RE: Paul , Chenh,

Thanks for the info. i will be starting to test it out in the next week or so and will update back to the forum here what my findings are. Thanks a lot :)

Sorry guys. no update yet. 2k8 project jump started. will update as it progress.

Any other people tried so far ? 

i mean for clustering SEP (any version)