Hello,
Check the NTP logs, there could have been attack hence the traffic from that machine is blocked for 10 minutes.
If you feel the traffic should be allowed, go to the Firewall policy ---> Protection and stealth settings--> uncheck 'Automatically block an attacker's IP address'
Since your proxy is the source IP, this is expected behaviour. SEP is not proxy aware.
To stop this, in SEPM go to your Firewall policy and go to the Protection and Stealth tab and uncheck this option: