Hello AhmedAli,
It states, "The Application and Device Control is designed for use on 32-bit operating systems. These steps will not help 64-bit clients. ", that's because in SEP 11.x, ADC does not work on 64 bit machines, however that's not the case with SEP 12.1.
So, this statement does not apply for SEP 12.1.
Hope that helps!!