There are three solution when you want to migrate SEPM to another machine.

1. if you can keep your new machine's IP address and host name the same as the old SEPM machine, you can refere the following KB "Best Practices for Disaster Recovery with the Symantec Endpoint Protection Manager":

http://service1.symantec.com/support/ent-security.nsf/docid/2007082112135948

2. if the new machine is different IP , you can use the two method:

1)use replication method to keep all policy the same with old SEPM's Policy, you can refer to

the following docs :

http://www.symantec.com/docs/TECH104389

2) if you don't want to do replication, you can fresh install new SEPM in new machine, and

replace sylink file to old SEP clients. How to Replace the sylink on the Client :

a. Copy of the file Sylink.xml from the server from C:\Program Files\Symantec\Symantec Endpoint Protection Manager\data\outbox\agent\

b. On the client computer , click Start > Run, type smc -stop, and click OK.

c. Copy the Sylink.xml into the C:\Program Files\Symantec\Symantec Endpoint Protection folder, and replace any existing Sylink.xml file.

d. Click Start > Run, type smc -start, and click OK.