What problem are you having? For example, SEP has the ability to block executables from running. Is that the problem? Or is it that after starting Wireshark no packets are being captured?
Are you running Wireshark on a Windows, Linux, etc? If Windows are you running it as administrator or a non-admin account?
What happens if you remove the firewall policy entirely - does Wireshark work correctly then?
Could fw rule #1 be preventing Wireshark from capturing any packets?