Hello,
As Per the Screenshot, the Policies are Locked from the Symantec Endpoint Protection Manager.
Please Follow the Steps provided below:
1) Open and Login to the Symantec Endpoint Protection Manager
2) Go to 'Clients' and Select the Right group to which the Client belong to / report to.
3) Click on 'Policies' Tab
4) Make sure the check box that says 'Inherit policies and Settings from parent group' is unchecked.
5) Double Click on Antivirus & Antispyware policy [Unshared]
6) Click on Edit shared Button
7) Uncheck on 'File System Auto Protect' or/and Unlock the Lock next to it.
8) Wait for few Seconds and then check the client.