Here the current product seleciton guide for 12.1:
https://www-secure.symantec.com/connect/articles/liveupdate-administrator-product-selection-guide
...please add as appropriate the 12.1 RU2 features - in an analogy to 12.1
2. What is "SEPM Virus Definitions Win32 12.1 RU2 H " ? What does H means
"H" are Hub defintiions for RU2 - you will need this if you want some of the clients get the definitions from SEPM.