Hello,
Configure the Disk space Management for Virus Def.
To configure the disk space used for LiveUpdate downloads
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In the console, click .
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Click and select the site that you want to configure.
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Under Tasks, click , and then click .
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Under Disk Space Management for Downloads, type the number of content downloads that you want to store.
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If you want to reduce the amount of disk space used, uncheck the option. Note: Disabling this option also disables the ability of Symantec Endpoint Protection Manager to construct deltas between content revisions and may adversely affect network performance for updates.
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Click .
Checlk these Articles:
Symantec Endpoint Protection (SEP) 12.1 client is maintaining multiple virus definitions versions on servers.
http://www.symantec.com/business/support/index?page=content&id=TECH180056
Disk Space Management procedures for the Symantec Endpoint Protection Manager
http://www.symantec.com/docs/TECH96214
Drive Space used by Virus Definitions Updates
http://www.symantec.com/docs/TECH141811
Hope that helps!!