http://eval.symantec.com/mktginfo/enterprise/white_papers/ent-whitepaper_veritas_netBackup_6.5_vmware_nov2007.pdf

the first doc to read is this whitepaper
then you can read this one:
http://eval.symantec.com/mktginfo/enterprise/other_resources/ent-technote_netbackup_for_vmware_configuration_08-2007.en-us.pdf

After that you should be able to design you configuration.

Peter

Assuming NetBackup and VMware (ESX 3.5 or 4.0?)

Software:
Recommend you update NetBackup components to 6.5.4 (since 6.5 there have been a lot of bug fixes and improvements made to performing 'VCB backups')
Recommend VMware ESX 3.5 Update 2 and above for VMware hosts. VCB 1.5 for VMware Consolidated Backup on a Windows 2003 Server proxy server. There is a update 1.5.1 if you want to use VCB with ESX 4.0 (vSphere)
The proxy server must have access to the storage that your VM's are located on.

License requirements:
http://seer.entsupport.symantec.com/docs/319255.htm

From VMware

Proven Practice: Setting Up VMware Consolidated Backup for any Backup Software
http://viops.vmware.com/home/docs/DOC-1392

From Symantec

Veritas NetBackup™ for VMware Administrator's Guide, version 6.5.4    
http://support.veritas.com/docs/318357
 

NetBackup 6.5 for VMware 3.x Best Practices (Rev.2/2009)
An updated paper that covers best practices for protecting and recovering data from VMware virtual machines.