1 In the console, click Admin.
2 On the lower left, click Servers.
3 Select the site you want to configure.
4 Under Tasks, click Edit Site Properties.
5 On the Log Settings tab, set the number of entries and number of days to
keep log entries for each type of log.
  You can reduce sizes for management server logs, client logs, and Enforcer logs.
6 Click OK.
 

Login toSEPM--> Admin---> Servers---> Local site properties--->Live
update settings--->Disk space management for download.
Reduce the number
of content as per ur need
I think you want to reduce the size of your database ,Am I right? 

this is reduce amount to data to DB but

i have reduce this file size

sem5_content.ndf still around 2.06 GB ....

???

i m using sql db on one server and this file grow too much and other i also want to reduce because
all files size are too much which all are

sem5_content.ndf   2.1GB
sem5.mdf  400+MB
sem5_log1.ldf    150 MB
sem5_log2.ldf  150 MB
sem5_index.ndf    409 MB
sem5_loginfo.ndf 360 MB
sem5_rptinfo.ndf 33 MB

Try by removing the
option for keep the virus definitions in the database option  in SEPM-->
Admin---> Servers---> Local site properties--->Live update
settings--->Disk space management for download and see any difference is present..

i did all
live update content
server properteis but SQL db and other files are same which are

sem5_content.ndf   2.1GB
sem5.mdf  400+MB
sem5_log1.ldf    150 MB
sem5_log2.ldf  150 MB
sem5_index.ndf    409 MB
sem5_loginfo.ndf 360 MB
sem5_rptinfo.ndf 33 MB

if only i can reduce sem5_content.ndf please help me out

i did all
live update content
server properteis but SQL db and other files are same which are

sem5_content.ndf   2.1GB
sem5.mdf  400+MB
sem5_log1.ldf    150 MB
sem5_log2.ldf  150 MB
sem5_index.ndf    409 MB
sem5_loginfo.ndf 360 MB
sem5_rptinfo.ndf 33 MB

if only i can reduce sem5_content.ndf please help me out

Increase the DB maintenance
You can set the DB maintenance to run more often under:
Admin --> Servers --> (Local Site) --> Edit Site Properties --> Database

You may also refer the below discussion  
https://www-secure.symantec.com/connect/forums/dat...

I think the files sizes are not huge...
Run this validation tool and find out whether database is correct or not.

Validation Tool for the Symantec Endpoint Protection Manager Database
http://service1.symantec.com/SUPPORT/ent-security....

If the database is correct then there is not problem with the size...
You have tried normal purge option so there will not be any new things to do.

  If Drive space is the issue the you may have to look at other possibilities. like liveupdate contents in SEPM etc...