<<<The systems must have Auto-protect diasbled and not turning on by default after a period of time.>>>
---It is possible in AV /AS policy uncheck file system autoprotect and clock the small lock symbol by clicking on it..It is not a recommended setting anyway.Do you have any particular reason for doing this?
<<Liveupdate should run on schedule to update definitions @ 4.00am on Mondays>>>
---It is possible if your liveupdate source is Internet or Internal LU server.(LU policy )
<<TruScan ProActive Threat Scan must be enabled>>>
---For this these features should be installed in the client
<<<Scheduled scan of only D drive.>>>
___It is possible if you are scheduling the scan in the client.Form SEPM through policies it is not possible.