Mostly, it should work just fine if you are using regular NTFS storage, since from DOS an NTFS filesystem is just an NTFS filesystem and there is nothing particularly special about Server 2003 at the NTFS level (striped/mirrored dynamic disk volume sets are one potential issue beneath the NTFS level, but generally that's not important for bare-metal recovery of boot partitions).
As long as your boot volume is a basic disk volume, and you can afford to reboot to DOS to do the imaging, GSS should be able to do that.
However, GSS doesn't do "hot" imaging using volume snapshot. For that, you'd need to use Backup Exec System Recovery (formerly LiveState Recovery), which is the "server" edition of the same Windows-based disk imaging used in the consumer
Norton Ghost 9 and 10 (which is completely different from the classic Ghost program used by GSS).