There is a self-help report (Scan for common issues) that details SEP Client to Manager communications. It performs the following tests:
1. Is the client a managed client?
2. Can we find a list of Managers for that client?
3. Can we resolve in DNS the managers listed as host names?
4. Can we communication with each manager?
The last two tests present a table summarizing the results for each manager.
This report should indicate a warning status if one or more managers cannot be communicated with and an error status if no managers can be communicated with.