@Chellapa - Only those clients were taking full zip updates from the SEPM which are having definitions older than 30 days as we have kept no. of revisions upto 90(which means content revisions of roughly 30 days and li'l more). Not all of the clients are going to SEPM. Rest of the clients are taking updates from their respective GUPs.
@Seyad - I totally agree with you. But, depite of that "Never" setting enabled, clients(having defs older than 30 days) were going to SEPM which are stopped now after checking the option "Prevent Clients from downloading full definition packages". So, I could say only one thing here like Chellapa said that there might be a possibility of bug in 12.1.5, which makes the sep clients(running with 12.1.5 version) to request full zip from SEPM(running at 12.1.6 version) and that has been prevented after checking the option "Prevent Clients from downloading full definition packages".
I have observed that the clients are going for full zip from SEPM as I have created a notification(at SEPM) for that if any client request a full zip from SEPM we would get a notification over email that the following clients has requested full defs. download from SEPM.