If you aren't concerned with potentially aborting some of your auto-starts that may be stuck in the queue, then it may help to:
- delete the specific project directory in IIS
- in workflow designer for your project - Plugins -> Reset Cache
- iisreset
- restart workflow extensions
- reload project (close and reopen)
- republish your project
- iisreset
- restart workflow extensions
then give it a shot. if this doesn't do anything, then it's likely a configuration issue and not a busted piece of workflow clogged in the gears someplace.
if you still can't get it working, let me know if you want to have a webex session and i'll take half an hour to look at it.
-andrew