Hi,
Thank you for posting in Symantec community.
What is the benefit for upgrade the version in 12.1 ru5?
--> Symantec Insight technology reduces antivirus scans while SONAR stops cyber-criminals and zero-day attacks. Only Symantec Endpoint Protection 12.1.5 provides the security you need through a single, high-powered agent, for the fastest, most-effective protection available.
Symantec Endpoint Protection is built on multiple layers of protection, including Symantec Insight and SONAR both of which provide protection against new and unknown threats. Built for virtual environments, it can integrate with VMware vShield Endpoint for dramatically improved performance. Symantec Endpoint Protection 12.1.4 includes the latest features for improved security, performance and management.
There are many benefits, few are listed here:
https://www-secure.symantec.com/connect/articles/feature-differences-between-sep-11x-and-sep-121
If you look specifically for SEP 12.1 RU5 new features, check these articles:
What's new in Symantec Endpoint Protection 12.1.
http://www.symantec.com/docs/HOWTO101747
Few GUI improvements I tried to list down here:
https://www-secure.symantec.com/connect/articles/whats-new-sepm-121-ru5-user-interface-differences
https://www-secure.symantec.com/connect/articles/whats-new-sepm-121-ru5-user-interface-differences-part-2
What is the change and effect for upgrade from 11.0.6?
--> Upgrade from 11.0.6 to SEP 12.1 RU5 is supported. After an upgrade you can get all use all the features listed above.