Hi jace5869,
I recommend cloning Drive 1. This "really is" your disk drive.
It is confusing, but Drive 80 isn't a real drive at all. It is the "OS volumes drive" under which Ghost will show all the volumes which the operating system recognises. This can be useful if you want to clone a volume (such as a RAID volume) which Ghost does not recognise. But Ghost won't clone the MBR or any other boot loader info from this drive.
If you need more help can you let us know: what version of Ghost this is, what the operating systems you are cloning are, and what the partitions are.
Cheers,