Will I need to still block the Autorun.inf files from running from the Symantec Device Control even though Windows 10 dropped the Autorun feature? Autorun was a security concern in Windows XP.
No, you shouldn't need to in cases where Windows OS dropped it. If you run SymDiag on the machine, one of the checks it does is to see if autorun is enabled, whic may help you in determing if you want to use the ADC policy or not.