In master server remove SEPM (including database) reinstall it
Follow this procedure for it
Best Practices for Disaster
Recovery with Symantec Endpoint Protection
Note:The first SEPM is like the "Master" server in the replication setup, and if it is uninstalled, the second SEPM has no ability to configure another replication partner.
After this add the second SEPM as replication parter. For this do as follows
Launch the Symantec Endpoint Protection Manager console.
Click the Admin tab. Under "View Servers", select a site.
Under "Tasks", click Add Replication Partner. The Add Replication Partner wizard appears.
Click Next on the "Welcome panel", and then enter the <IP Address> or <Host name> of the server that you wish to add as a replication partner.
Enter the <port number> and the administrator's user name and password for the remote server on which you installed the SEPM.
Note: The default setting for the remote server port is 8443.
Click Next to invoke the "Schedule Replication" dialog box
Disable "Autoreplicate" to set up a custom schedule for replication:
Select the hourly, daily, or weekly Replication Frequency.
Select the specific day during which you want replication to occur in the Day of Week list to set up a weekly schedule.
Click Next when the replication schedule is configured as desired.
Click Yes or No depending on whether or not you want to replicate logs.
Note: The default setting is No.
Click Next and then click Finish. The replication partner site is added under Replication Partners on the Admin page.
Ref:
How to add "Replication Partners" and Schedule Replication