Hi,
Thank you for posting in Symnatec community.
Is there any replication configured?
You must turn off replication before you attempt to uninstall a Symantec Endpoint Protection Manager that is set up for replication. After you turn off replication, you can restart the computer from which you want uninstall the Symantec Endpoint Protection Manager, and then you can perform the uninstallation.
To uninstall Symantec Endpoint Protection Manager
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On the server computer, on the Start menu, click .
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In the Add or Remove Programs dialog box, select , and then click .