Yes, can use Sepprep.ini to unisntall other AV.
SEPprep is an unsupported tool that is designed to uninstall any competitive product automatically. This tool can also launch another application before or after removing all competitive products.
What if the third-party product is not in the supported products list?
Security products that are not in the supported products list can be removed using the SEPprep tool.
Reference: http://www.symantec.com/docs/TECH178757