How can i disable the tamper protection from unmanage sep client or from manage sep client?

Uncheck the tamper setting under client management.

How to disable Tamper Protection in Symantec Endpoint Protection 12.1

Enabling, disabling, and configuring Tamper Protection in Endpoint Protection on unmanaged Clients

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Setting from unmanage client

1. Open SEP
2. Click Change Settings
3. Click Configure Settings (next to Client Management)
4. Click the Tamper Protection tab
5. Perform one of the following actions:
   1. Uncheck Protection Symantec security software from being tampered with or shut down. This disables Tamper Protection.
   2. Change the dropdown menu to Log only.  Note: This setting leaves Tamper Protection enabled, however, Tamper Protection will no longer block attempts to modify SEP's files, folders, processes, and Registry values.
6. Click OK. Tamper Protection is now disabled for this SEP client.

How to disable Tamper Protection within the Symantec Endpoint Protection Manager (SEPM) Enterprise Edition console:

Note: This option is best if you need to disable Tamper Protection for a large number of clients.

1. Open the SEPM console
2. Click Clients
3. Select the client-group you want to modify
4. Click the Policies tab
5. Click General Settings
6. Click the Tamper Protection tab
7. Perform one of the following actions:
   1. Uncheck Protection Symantec security software from being tampered with or shut down. This disables Tamper Protection.
   2. Change the dropdown menu to Log only.  Note: This setting leaves Tamper Protection enabled, however, Tamper Protection will no longer block attempts to modify SEP's files, folders, processes, and Registry values.
8. Click OK. Tamper Protection will be disabled for clients within this client-group and clients within client-groups which inherit policies from this group as soon as they receive the updated policy from the SEPM.

Hi,

Enabling, disabling, and configuring Tamper Protection in Endpoint Protection on unmanaged Clients

http://www.symantec.com/business/support/index?page=content&id=TECH102688&key=56824&actp=LIST

Open the GUI

Change Settings

Under Client Management select Configure Settings

Select the Tamper Protection tab and uncheck the box.

Click OK to save the change.