Hello,
In your case if your machine is severely infected and the above steps does not work for you - my advice for you would be below -
1) Physically moving the hard drive to another system with AV installed and then running a full scan.
2) Mapping the drive and scanning across an isolated network connection.
3) In case the machine is Virtual machine, you may try to revert the snapshot to the older version.
4) In case of Physical machine, you may like to perform either a restore from your backup OR reimage of the machine.
It is advisable to have a backup of your assets / information of data.
Regards,