The above are all good possible solutions to the problem.
Make sure NTP is not running on any servers. I prefer just AV only myself
Exclude the image file type from auto-protect
disable any network file scans
And finally, perhaps if you must have NTP, create a rule to either allow iSCSI traffic and/or create a signature for IPS to not scan iSCSI traffic
Or another firewall rule would be an any<>any rule for that iSCSI adapter.