You can use any machine you want.
As long as you remember that that machine is now your new 'gold' image.
I have installed the OS, all application that were required, all tools and utilities and all patches for that OS and those apps, etc, and then run VIE tool
And if your VM is infected with something, that will cause all other images to be infected as well... Like any normal cloning process.
And the question remains: do you actually gain that much by using the VIE tool?
Or do you prefer the security that comes by not using the VIE tool?
Up to each individual.
Just my $0.03
*inflation added to the normal $0.02