You need to export Sylink from SEPM and run Sylink replacer on one machine.
You need to mention either the subnet range or need to have a text file with all IPs in it.
Running Sylink Replacer from one machine will help you to replace sylink on all other machines.
You dont need to execute the tool individually on each machine.
-The Sylinkreplacer tool for connecting SEP clients to a SEPM
https://www-secure.symantec.com/connect/downloads/sylinkreplacer-tool-connecting-sep-clients-sepm