The following is from the PGP Desktop 10.2 for Windows User's Guide:
Calculate the Encryption Duration
Encryption is a time-consuming and CPU-intensive process. The larger the disk or partition being encrypted, the longer the encryption process takes. You should consider this as you schedule initial encryption of the disk.
Factors that may affect encryption speed include:
• the size of the disk or partition
• the processor speed and number of processors
• the number of system processes running on the computer
• the number of other applications running on the system
• the amount of processor time those other applications require
With an average system, an 80 GB boot disk or partition takes approximately three hours to encrypt using PGP Whole Disk Encryption (when no other applications are running). A very fast system, on the other hand, can easily encrypt such a disk or partition in less than an hour.
You can still use your system during encryption. Your system is somewhat slower than usual during the encryption process, although it is fully usable.
PGP Desktop automatically slows the encryption process if you are using the system. The encryption process is faster if you avoid using your computer during the initial encryption. The system returns to normal operation when the encryption process is complete.
If you decide to run other applications during the encryption process, those applications will probably run slightly slower than normal until the encryption process is over.
If you will not be using the computer during encryption, you can speed up initial encryption using the Maximum CPU Usage option, described in Setting Encryption Options (on page 136). The extra speed during encryption comes primarily by taking priority over other operations that your computer is performing.