Upgrade to the latest version of endpoint i.e. RU 5.
You can download it from
https://fileconnect.symantec.com/licenselogin.jsp?localeStr=en_US
These tmp files could also be related to the following issue which is fixed in RU 5.
TMP folders in virus definitions folder eventually consume all available drive space
Fix ID: 1177176
Symptom: Symantec Endpoint Protection clients create tmp folders in the C:\Program Files\Common Files\Symantec Shared\VirusDefs folder. When new definitions arrive, the problem stops, but starts again at random times on some computers. TMP folders are created in 5 and 10 minute intervals, eventually consuming all available space on the drive.
Solution: LiveUpdate code modified to clean up temporary folders and registry values in the case of failures during the update process.