Intelligent Updater:
Here is the link to the TechNote for it, which also contains two links to the downloads (one for 12.x and one for 14.x). Once on the downloads page, make sure you click the link for the appropriate version (x86, x64, etc).
https://support.symantec.com/en_US/article.TECH102606.html
After you download the updater, it couldn't be easier. Copy it to the local machine or a network share, if you will have access to it from the machine you will boot into Safe Mode with Networking. Run the executable, it will ask you if you want to check for updates to the version of Symantec Endpoint Client that's installed - choose Yes - and within 15 seconds it will tell you it finished. The installed client generally reflects the new definitions within 30 seconds after that.
Only thing left to do is reboot, and you're fixed. The updater made fixing the problem servers easy but it still took all day for us to resolve everything - we chose to be over cautious and check each individual Server 2008 machine to be on the safe side.
Glad this particular incident is over.