Hi Brian,
Just to get the situation revised, the issue is why Symantec client going to proxy server for definitions because of which proxy server is getting number of request.
As we have SEPM in a network, so SEP client should directly come to SEPM server for definitions if they are connected to a network but still they are coming to SEPM server via proxy.
In the proxy, we have bypassed the domain and also IP ranges but still is the issue, also further checked with our network team clients are taking below URL and going to the proxy.
"http://sep12-pw10.ec.win.colpal.com/content/{810D5A61-809F-49c2-BD75-177F0647D2BA}/170320054/xdelta170320054_To_170321004.dax"
where sep12-pw10.ec.win.colpal.com is our internal server where in proxy *.colpal.com is already bypassed.
So the question is why SEP client is going to the proxy , this was not happening previously.Do we need to change any settings on SEPM level or Proxy level?