Hi,
Thank you for posting in Symanec community.
I would be glad to answer your query.
Q. Has anyone uncovered any interesting issues with it? (Thinking along the lines of the last update and the network performance decrease it brought about, or any other issues?)
--> I haven't seen any reported issue on Symantec community. Need to check with SEP queue if they have come across any known issue.
As a best practice test few clients with the latest version and share the results.
RU3 has released on 6th June'13 & may be it may take some time to report the new issue if there would be any.