No, you must manage 14.0.1 (RU1) clients with a 14.0.1 (RU1) SEPM. This is stated in the release notes, under Client Information on page 14.
http://www.symantec.com/docs/DOC10647
SEPM 14, 14 MP1, and 14 MP2 cannot manage 14 RU1 clients and there is no workaround for it.