Seems like Network threat protection is causing the issue.
NTP is the firewall component not recomemded on ISA as per the above links.
Please remove this and install just AV and AS
Please remove NTP from add / remove programs
go to add / remove programs
select SEP
click on Modify
Uncheck NTP , just keep AV and AS
install it ...
it will have just AV now no firewall component.
This should fix the issue.