Hi,
It is quite possible that all Microsoft patches are installed. However, what about patches for toher softwares for example Adobe. The CVE website talks about some vulnerabilities related Microsoft, Sun Java, Adobe PDF.
Perform a Vulnerability assessment using automated tools. You can use automated tools to scan your network for vulnerabilities. You can scan for IP addresses and get granular to port numbers and protocols as well (TCP or UDP). These tools have updated information of vulnerabilities. Below are some tools. Nessus can be used for free for non commercial use.
Please ensure that the tool used to scan vulnerabilities is updated.
IBM ISS: http://www.iss.net/
Nessus : http://www.tenable.com/products/nessus
Core Impact http://www.coresecurity.com/content/core-impact-ov...
SAINT http://www.saintcorporation.com/
SARA http://www-arc.com/sara/
I have used Nessus, it is quite simple tool.
Here are some sites that provide information of the latest vulnerabilities.
Common Vulnerability Database http://cve.mitre.org/
Security focus http://www.securityfocus.com/
DHS National Vulnerability Database http://nvd.nist.gov
United States Computer Emergency Readiness Team http://www.us-cert.gov/
Open Source Vulnerability Database http://osvdb.org/