Hello,
Check these Articles on how to configure SEP to block software.
Block Software By Fingerprint
https://www-secure.symantec.com/connect/articles/block-software-fingerprint
How to use Symantec Endpoint Protection to block or log legitimate but unauthorized software usage
http://www.symantec.com/docs/TECH97618
Configuring system lockdown
http://www.symantec.com/docs/HOWTO80848
Automatically updating whitelists or blacklists for system lockdown
http://www.symantec.com/docs/HOWTO81094
In case, you want to Whitelist an Application, then check this Article:
Software developer would like to add his/her software to the Symantec White-List.
http://www.symantec.com/docs/TECH132220
For software developers, authors, and Independent Software Vendors (ISVs), the Symantec Software White-List program offers an opportunity to have their software added to a white-list of known good software maintained by Symantec to reduce the possibility of false positives.
To submit software to participate in this program, please submit the candidate software to Symantec using the Software White-Listing Request form.
Software White-Listing Request Form: https://submit.symantec.com/whitelist/
Secondly, there are 3 other things you could also do-
1) Report a Suspected Erroneous Detection and Report a Suspected Erroneous Detection (False Positive) https://submit.symantec.com/false_positive/
Your selections:
• Detection occurred: While using an application
• Using product: Symantec Endpoint Protection 12.x
• Type of detection: SONAR (Behavioral Heuristics Detection)
2) Sign your files with Class-3 digital certificates (X.509) from a Certificate Authority if you need to publish softwares/files.
3) Also participate in white-listing program if needed http://www.symantec.com/docs/TECH132220
Hope that helps!!!