The guide is specific to the OS that you're using as well. Stop the smc service first (smc -stop)
Delete user temp
Windows Vista/7/2008/8/2012/10:
DEL /F /Q "C:\Users\NAMEOFUSER\AppData\Local\Temp"
Deleting the contents of the temp folder at the root of C:\
Type the following command in Command Prompt:
DEL /F /Q C:\temp
Deleting the contents of the Windows Temp folder
Type the following command in Command Prompt:
DEL /F /Q C:\WINDOWS\Temp
Are you on 12.1.5 or higher or a lwer version?
Symantec Endpoint Protection 12.1.5+
DEL /F /Q C:\Documents and Settings\All Users\Application Data\Symantec\Defwatch.DWH
Windows Vista/7/2008/8/2012/10:
Symantec Endpoint Protection 12.1.5+
DEL /F /Q C:\ProgramData\Symantec\Defwatch.DWH
Deleting the contents of the xfer and/or xfer_temp folders
Type the following command in Command Prompt. Replace silo with the appropriate build number:
Symantec Endpoint Protection 12.1
DEL /F /Q "C:\ProgramData\Symantec\Symantec Endpoint Protection\silo\Data\xfer_tmp\"
DEL /F /Q "C:\ProgramData\Symantec\Symantec Endpoint Protection\silo\Data\xfer\"
Delete the Quarantine Folder
Type the following commands in the Command Prompt. Replace silo with the appropriate build number:
Symantec Endpoint Protection 12.1
DEL /F /Q "C:\ProgramData\Symantec\Symantec Endpoint Protection\silo\Data\Quarantine\"
RD /S /Q "C:\ProgramData\Symantec\Symantec Endpoint Protection\silo\Data\Quarantine\"
Symantec Endpoint Protection 12.1
MD "C:\ProgramData\Symantec\Symantec Endpoint Protection\silo\Data\Quarantine\"
Start the smc service (smc -start)