Hello,
In case you are running Symantec Endpoint Protection 12.1 SBE, in that case, the on-premises version of the SEP SBE product has reached End-of-Life status https://support.symantec.com/en_US/article.DOC8217.html). This means that there will be no further updates - including updates to support Windows 10.
https://support.symantec.com/en_US/article.DOC8919.html
Here is an URL (https://www.symantec.com/page.jsp?id=sbe-migration) which does include instructions on how you can migrate your SEP SBE On-Premises clients and policies into the Hosted (or .Cloud) version of the product.
Note: This does NOT mean the customer needs to immediately upgrade their product. Customers will be able to renew their on-premises license and continue to use their SBE SEPM’s until 2018.http://www.symantec.com/docs/TECH215058
But Small Business Edition 12.1 RU5 (12.1.5337.5000) is not compatible with Windows 10 OS & there is no release planned for this edition, either upgrade/migrate to Enteprise Edition or SBE.cloud to to receive Windows 10 support.
Additionally you can purchase the Enterprise version of the product and also do an in-place upgrade. (https://support.symantec.com/en_US/article.TECH163700.html). As of the time of writing this there is a discount for SBE customers to upgrade to enterprise.
If you are interested in upgrading from SBE to Enterprise please contact our Sales group at 1 (800) 745-6054 and request to speak with Renewals.
You may like to check this article as well -
Windows 10 support for the Cloud version of Endpoint Protection Small Business Edition
https://support.symantec.com/en_US/article.DOC8908.html
Regards,