Hello,
I can give you feedback on Windows 10 (anniversary version) with 14.6v. Been testing for a while and didnt identifyy any issues. Working flawless with IE 11, latest Chrome version and Office 2016. Ddidnt try Edge but its supported as well on DLP 14.6 (in terms of incident detection).
In case you are using Windows 10 with windows creators update there are some known issues/conflict with Symantec DLP.
BR,
Morgado