Depending on the situation you are attempting, there are some things you can do via DS.
The easiest is probably to replace the hosts file with one that redirects all requests to domain controllers or the domain to 127.0.0.1. This would probably mean that you would have to do your install as a local administrator as the domain wouldn't be available for authentication.
An example would be:
If your domain controllers are dc1, dc2 and dc3 and the domain name is domain.local (i.e. dc1.domain.local, etc.), your hosts file might look like this:
domain.local 127.0.0.1
dc1 127.0.0.1
dc2 127.0.0.1
dc3 127.0.0.1
dc1.domain.local 127.0.0.1
dc2.domain.local 127.0.0.1
dc3.domain.local 127.0.0.1
I can't say for certain this would work though, so you would have to test it out. To remove the DNS servers from your TCP config, you could do a configure computer job in DS.
You can't enable/disable policies on the fly via DS for the domain though, that would be something that your administrators would have to do for you.
Another note, however, if you are doing this as part of a build, you might consider doing the software install prior to joining the computer to the domain, thus the policies wouldn't be pushed down at that point.